3,3′-Di-Indole Methane
$160.91
| Size |
5g |
|---|
CAS #
1968-05-4
Concentration
98.00%
Description
3,3′-Di-Indole Methane is an acid-catalyzed reaction product of a phytochemical naturally found in Brassicaceae, indole-3-carbinol. It functions as an antitumor agent. This derivative can both directly stimulate apoptosis at relatively high concentrations and sensitize TRAIL-induced apoptosis in human cancer cells. DIM induces a G1 cell cycle arrest in human breast cancer MCF-7 cells by a mechanism that includes increased expression of p21. DIM is a strong mitochondrial H+-ATPase inhibitor.
Keywords
3,3′-Bisindolylmethane, DIM, Arundine, HB 236
MAECENAS IACULIS
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ADIPISCING CONVALLIS BULUM
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