CYP4V2 Antibody

Aliases Cytochrome P450 4V2, Docosahexaenoic acid omega-hydroxylase CYP4V2Curated, CYP4V2 Antibody Type Polyclonal Species Human Uniprot ID Q6ZWL3 Immunogen Recombinant human Cytochrome P450 4V2 protein (246-525AA) Raised In Rabbit Species Reactivity Human Tested Applications ELISA, WB, IHC;Not yet tested in other applications. Background / Function Omega-hydroxylase that oxidizes medium-chain saturated fatty acids and polyunsaturated omega-3 fatty acids, and which plays a role in fatty acid and steroid metabolism in the eye (PubMed:19661213, PubMed:22772592). Catalyzes the omega-hydroxylation of medium-chain saturated fatty acids such as laurate, myristate and palmitate in an NADPH-dependent pathway. The substrate specificity is higher for myristate > laurate > palmitate (C14>C16>C12) (PubMed:19661213). Acts as a polyunsaturated omega-3 fatty acids hydroxylase by mediating oxidation of docosahexaenoate (DHA) to 22-hydroxydocosahexaenoate (PubMed:22772592). Also produces some 21-hydroxydocosahexaenoate. Also converts eicosapentaenoate (EPA) to 20-hydroxyeicosapentaenoate (20-OH-EPA) (PubMed:22772592). Isotype IgG Conjugate Unconjugated Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form Liquid Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze. Purity Antigen Affinity Purified Modification Cytochrome P450 4V2