SENP1 Antibody, Biotin conjugated

Aliases Sentrin-specific protease 1, Sentrin/SUMO-specific protease SENP1, SENP1 Antibody Type Polyclonal Species Human Uniprot ID Q9P0U3 Immunogen Recombinant Human Sentrin-specific protease 1 protein (63-214AA) Raised In Rabbit Species Reactivity Human Tested Applications ELISA Background / Function Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjugates SUMO2 from MTA1. Desumoylates CCAR2 which decreases its interaction with SIRT1 (PubMed:25406032). Isotype IgG Conjugate Biotin Storage Buffer Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form Liquid Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze. Purity >95%,Protein G purified Modification Sentrin-specific protease 1