Carbenicillin disodium
Price range: $43.99 through $542.93
| Size |
1 g ,5 g ,25 g ,50 g |
|---|
General Description
Carbenicillin is a broad-spectrum antibiotic, which inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. It is semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. It acylates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis.
Synonyms:Â Â Â Â Â Â Â Â Â Â Â Carbenicillin sodium, Carbecin, Sodium carbenicillin, Carbenicillin, Carboxybenzyl Penicillin, Disodium Carbenicillin, Geopen, Microcillin, Pyopen, Carbapen
CAS Number:Â Â Â Â Â Â Â Â Â 4800-94-6;
Molecular Formula:Â Â Â C17H16N2Na2O6S
Molecular Weight:Â Â Â Â 422.363
Features:Â
1. Used for selection of ampr transformed cells.
2. Used to study the role of penicillin-sensitive transpeptidases in cell wall biosynthesis.
3.  Antimicrobial spectrum: Gram-positive and Gram-negative bacteria, Pseudomonas.
MAECENAS IACULIS
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ADIPISCING CONVALLIS BULUM
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Sodium acetate, pH 5.2 [3M]
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