Antipain dihydrochloride

$115.76$393.58

Antipain dihydrochloride is a protease inhibitor, originally produced by actinomycetes.

Size

5 mg

,

10 mg

,

25 mg

SKU: 10463 Categories: ,
Description

General Description

Antipain dihydrochloride is a protease inhibitor, originally produced by actinomycetes. It reversibly inhibit serine/cysteine proteases (cathepsin A, B, and D as well as papain) and some trypsin and trypsin-like serine proteases. Its action resembles leupeptin; however, its plasmin inhibition is less and its cathepsin A inhibition is more than that observed with leupeptin. Chronic administration of antipain can reduce the frequency of chemically induced transformation in BALB/c-/3T3 cells. Antipain acts by forming a hemiacetal adduct between the aldehyde group of the inhibitor and the active serine of the proteinase. Effective at concentrations range from 1 to 100 μM.

 

Molecular Formula:      C27H44N10O6.2HCl

Molecular weight:         677.62

CAS Number:                 37682-72-7

Appearance:                   White to off-white solid

Solubility:                        Water (> 50 mg/ml) or DMSO (5 mg/ml)

Purity:                              ≥97% by HPLC

Storage:                           Store at -20 ℃. Protect from light and moisture

 

Manual
Safety Datasheet

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Certificate of Analysis

Certificate of Analysis

Shipping & Delivery

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