![BSOCOES (Bis [2-(Succinimidooxycarbonyloxy)ethyl] Sulfone)](https://proteogene.com/wp-content/uploads/2019/02/BSOCOES.jpg "BSOCOES (Bis [2-(Succinimidooxycarbonyloxy)ethyl] Sulfone)")
BSOCOES (Bis [2-(Succinimidooxycarbonyloxy)ethyl] Sulfone)
$384.33
| Size |
100 mg |
|---|
General Description
BSOCOES is a homobifunctional N-hydroxysuccimide (NHS) ester crosslinker with a base-cleavable spacer arm for reversible crosslinking between primary amines, that successfully forms covalent bonds with molecules having primary amines such as peptides and proteins. The spacer arm in BSOCOES contains a sulfone bond, which can be cleaved with alkaline conditions to reverse the linkage.
Molecular Weight: 436.36
Spacer Arm Length: 13.0Å
Formula: C14H16N2O12S
Features of BSOCOES:
- Reactive groups – NHS ester (both ends)
- Reactive towards – amino groups (primary amines)
- Base – cleavable (pH 11.6, 2 hours, 37°C)
- Water- insoluble (dissolve first in DMF or DMSO)
- Membrane- permeable, allowing for intracellular crosslinking
MAECENAS IACULIS
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ADIPISCING CONVALLIS BULUM
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