Caspase 2, Human Recombinant
$463.05
| Size |
25 Units |
|---|
Caspase 2, Human Recombinant
General description
Caspase-2 (also known as Ich-1, Nedd-2) is a member of the caspase-family of cysteine proteases. Similar to other caspases, Caspase-2 also exists in cells as an inactive proenzyme. During apoptosis pro-caspase-2 is processed at aspartate residues by self-proteolysis and/or cleavage by upstream caspases. The processed active Caspase-2 is a heterotetrametric molecule consisting of two large (19 kDa) and two small (12 kDa) subunits. The recombinant active human Caspase-2 was expressed in E. coli. The active Caspase-2 preferentially cleaves Caspase-2 substrates (e.g., VDVAD-AFC or VDVAD-pNA).
Synonyms:Â Â Â Â Â Â Â Â Â Â Â Â Caspase-2, CASP-2, Neural precursor cell expressed developmentally down-regulated protein 2, NEDD-2, Protease ICH-1
Gene Symbol:Â Â Â Â Â Â Â Â Â Â CASP2
Gene ID:Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â 835
Source:Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â E. coli.
Form:Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Lyophilized powder
Molecular Weight:Â Â Â Â Â Â Two large (19 kDa) and two small (12 kDa) subunit
Reconstitution Inst.:     Reconstitute to 1 unit per µl in PBS containing 15% glycerol
Handling:Â Â Â Â Â Â Â Â Â Â Â Â Â Â Centrifuge the vial prior to opening
Storage temp.:         -70°C
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MAECENAS IACULIS
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ADIPISCING CONVALLIS BULUM
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