Caspase-3, 7, 10 Inhibitor (Z-DEVD-FMK) [1mM]

$156.28

Size

100 µl

Description

Caspase Inhibitors, Caspase 3, 7 Inhibitor, fluoromethyl ketone, FMK

General description

It is a synthetic peptide that irreversibly inhibits activity of DEVD-dependent caspases (e.g., Caspase-3 and Caspase-7) and blocks apoptosis. The inhibitor is designed as a methyl ester to facilitate cell permeability, and the product can be used for both in vitro and in vivo studies. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

Synonyms: Z-DEVD-FMK, Z-DEVD-fluoromethylketone, Caspase-3 inhibitor (fluoromethylketone)

Peptide Sequence: Z-Asp (OMe)-Glu (OMe)-Val-Asp (OMe)-FMK

Appearance: Lyophilized solid

Molecular Formula: C₃₀H₄₁FN₄O₁₂

Molecular Weight: 668.7

Solubility: DMSO (20 mM)

InChi Key: GBJVAVGBSGRRKN-JYEBCORGSA-N

PubChem CID: 16760394

Handling: Protect from light and moisture

Storage temp.: -20°C

Manual

Safety Datasheet

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Certificate of Analysis

Shipping & Delivery

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