Caspase 4, Human Recombinant

Caspase 4, Human Recombinant

General description

Caspase-4 (also known as Ich-4, ICErelII, TX) is a member of the caspase-family of cysteine proteases. Similar to other caspases, Caspase-4 exists in cells as an inactive proenzyme which is matured by proteolysis to yield large and small subunits. The active Caspase-4 is a heterotetrametric molecule consisting of two large and two small subunits. To date the mechanism of Caspase-4 activation and roles of Caspase-4 in apoptosis are poorly understood. The recombinant active human Caspase-4 was expressed in E. coli.

Synonyms:                        Caspase-4, CASP-4, ICE (rel)-II, Protease ICH-2, Protease TX

Gene Symbol:                   CASP4

Gene ID:                            837

Source:                              E. coli.

Form:                                 Lyophilized powder

Reconstitution Inst.:       Reconstitute to 1 unit per µl in distilled H2O

Handling:                          Centrifuge the vial prior to opening

Storage temp.:                 -70°C