Caspase 6, Human Recombinant
$463.05
| Size |
25 Units |
|---|
Caspase 6, Human Recombinant
General description
Caspase-6 (also known as Mch2) is a member of the caspase-family of cysteine proteases. Similar to other caspases, Caspase-6 also exists in cells as an inactive proenzyme. During apoptosis procaspase-6 is processed at aspartate residues by self-proteolysis and/or cleavage by another caspase. The processed active form of Caspase-6 consists of large (18 kDa) and small (11 kDa) subunits which associate to form the active enzyme. Active Caspase-6 has been shown to be of importance in the proteolysis of PARP (poly ADP-ribose polymerase), an enzyme that is involved in DNA repair and genomic maintenance. The recombinant active human Caspase-6 was expressed in E. coli.
Synonyms:Â Â Â Â Â Â Â Â Â Â Â Â Caspase-6, CASP-6, Apoptotic protease Mch-2
Gene Symbol:Â Â Â Â Â Â Â Â Â CASP6
Gene ID:Â Â Â Â Â Â Â Â Â Â Â Â Â Â 839
Source:Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â E. coli.
Form:Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Lyophilized powder
Molecular Weight:Â Â Â Â Â Â Large (18 kDa) and small (11 kDa)
Reconstitution Inst:       Reconstitute to 1 unit per µl in PBS containing 15% glycerol
Handling:Â Â Â Â Â Â Â Â Â Â Â Â Â Centrifuge the vial prior to opening
Storage temp.:         -70°C
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MAECENAS IACULIS
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ADIPISCING CONVALLIS BULUM
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