COL10A1 Antibody

Aliases COL10A1 Antibody Type Polyclonal Antibody Species Human Uniprot ID Q03692 Immunogen Recombinant human Collagen alpha-1(X) chain protein (521-680AA) Raised In Rabbit Species Reactivity Human Tested Applications ELISA, WB, IHC;Recommended dilution:WB:1:500-2000, IHC:1:20-1:200 Background / Function Type X collagen is a product of hypertrophic chondrocytes and has been localized to presumptive mineralization zones of hyaline cartilage. Isotype IgG Conjugate Unconjugated Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form Liquid Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze. Purity Antigen Affinity Purified Literature [1]”Mutations of COL10A1 in Schmid metaphyseal chondrodysplasia.”Bateman J.F., Wilson R., Freddi S., Lamande S.R., Savarirayan R.Hum. Mutat. 25:525-534(2005). [2]”Novel missense mutation resulting in the substitution of tyrosine by cysteine at codon 597 of the type X collagen gene associated with Schmid metaphyseal chondrodysplasia.”Sawai H., Ida A., Nakata Y., Koyama K.J. Hum. Genet. 43:259-261(1998). [3]”Mutation of the type X collagen gene ‘COL10A1’ causes spondylometaphyseal dysplasia.” Ikegawa S., Nishimura G., Nagai T., Hasegawa T., Ohashi H., Nakamura Y.Am. J. Hum. Genet. 63:1659-1662(1998).