LIPA Antibody

Aliases Cholesteryl esterase Lipase A Sterol esterase LIPA Antibody Type Polyclonal Antibody Species Human Uniprot ID P38571 Immunogen Recombinant human Lysosomal acid lipase/cholesteryl ester hydrolase protein (22-399AA) Raised In Rabbit Species Reactivity Human;Other species are not tested.Please decide the specificity by homology Tested Applications ELISA, WB Background / Function Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation. Isotype IgG Conjugate Unconjugated Storage Buffer Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form liquid Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze. Purity Caprylic Acid Ammonium Sulfate Precipitation purified Research Metabolism Literature [1]Cloning and expression of cDNA encoding human lysosomal acid lipase/cholesteryl ester hydrolase. Similarities to gastric and lingual lipases.Anderson R.A., Sando G.N.J. Biol. Chem. 266:22479-22484(1991) [2]Purification, characterization and molecular