MCM9 Antibody

Aliases DNA helicase MCM9 (EC:3.6.4.12), hMCM9, MCM9, C6orf61, MCMDC1, Mini-chromosome maintenance deficient domain-containing protein 1, Minichromosome maintenance 9 Antibody Type Polyclonal Antibody Species Human Uniprot ID Q9NXL9 Immunogen Recombinant human DNA helicase MCM9 protein (1-391AA) Raised In Rabbit Species Reactivity Human;Mouse Tested Applications ELISA, WB, IHC;Recommended dilution:WB:1:500-2000, IHC:1:20-1:200 Background / Function Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart. Isotype IgG Conjugate Unconjugated Storage Buffer Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form Liquid Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze. Purity Caprylic Acid Ammonium Sulfate Precipitation purified