Novobiocin sodium salt
$174.80 – $658.69
| Size |
5 g ,10 g ,25 g |
|---|
General description
Bacterial DNA gyrase is a heterodimeric type II topoisomerase that negatively supercoils circular double-stranded DNA. Novobiocin is a coumarin antibiotic, first isolated from Streptomyces species, that inhibits the ATPase activity of DNA gyrase. Its antibacterial activity arises from competitive inhibition of the ATPase reaction catalyzed by the GyrB subunit. In addition to permitting relaxation of negative supercoils, novobiocin has been used to generate positively supercoiled DNA. It also inhibits the chaperone activity of Hsp90 (IC50 = 700 mM).
Synonyms:Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Albamycin (TN), NSC 2382
CAS No.:Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â 1476-53-5
Molecular Formula:       C31H35N2O11 • Na
Molecular Weight:Â Â Â Â Â Â Â Â 634.6
Purity:                  ≥95%
Formulation:Â Â Â Â Â Â Â Â Â Â Â Â Â A crystalline solid
λmax:                  212, 249, 307 nm
InChi Key:Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â WWPRGAYLRGSOSU-RNROJPEYSA-M
Storage temp.:          -20°C
[vc_row][vc_column][vcex_button url=”`{`acf field=“safety“`}`” size=”large” text_source=”custom_text” aria_label=”Safety Datasheet” target=”blank” icon_left=”ticon ticon-file-pdf-o” icon_left_padding=”10px”]Safety Datasheet[/vcex_button][/vc_column][/vc_row]
MAECENAS IACULIS
Vestibulum curae torquent diam diam commodo parturient penatibus nunc dui adipiscing convallis bulum parturient suspendisse parturient a.Parturient in parturient scelerisque nibh lectus quam a natoque adipiscing a vestibulum hendrerit et pharetra fames nunc natoque dui.
ADIPISCING CONVALLIS BULUM
- Vestibulum penatibus nunc dui adipiscing convallis bulum parturient suspendisse.
- Abitur parturient praesent lectus quam a natoque adipiscing a vestibulum hendre.
- Diam parturient dictumst parturient scelerisque nibh lectus.
Scelerisque adipiscing bibendum sem vestibulum et in a a a purus lectus faucibus lobortis tincidunt purus lectus nisl class eros.Condimentum a et ullamcorper dictumst mus et tristique elementum nam inceptos hac parturient scelerisque vestibulum amet elit ut volutpat.
Related products
Agar, Bacteriological Grade
$51.82 – $360.02
Agarose I, All Purpose, Low EEO
$78.72 – $542.93
Ammonium acetate
$26.63 – $84.51
Bicinchoninic acid; BCA
$282.46 – $686.47
Bis (N,N’-methylenebisacrylamide)
$69.46 – $270.88
Blasticidin
$193.32 – $464.21
Calcium chloride dihydrate; (CaCl2.2H2O)
$52.09 – $99.56
