SMPB (Succinimidyl 4-(p-maleimidophenyl)Butyrate)
$267.41
| Size |
50 mg |
|---|
General Description
SMPB is Succinimidyl 4-(p-maleimidophenyl)Butyrate, a heterobifunctional crosslinkers that contain N-hydroxysuccinimide (NHS) ester and maleimide reactive groups that permit covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at alkaline pH 7-9 to form amide bonds, while maleimides react with sulfhydryl groups at acidic pH 6.5-7.5 to form stable thioether bonds.
Â
Molecular Weight:Â Â 356.33
Spacer Arm:Â Â Â Â Â Â Â Â 11.6Ã…
Features of SMPB:
1. Reactive groups: NHS ester and maleimide
2. Reactive towards: amino and sulfhydryl groups
3. Non-cleavable
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MAECENAS IACULIS
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